Wednesday, 13 May 2020

Brief on side effects of Atazanavir Sulphate

side effects of atazanavir sulphate

Atazanavir sulphate is an antiretroviral medication that is used in the prevention and treatment of HIV or AIDS. It is generally used in combination with other antiretroviral medications. The efficiency of atazanavir is known by antiretroviral therapy (ART) treatment.

Atazanavir sulphate works by binding HIV protease and inhibiting it's for the synthesis and multiplication.

Side effects of Atazanavir Sulphate: 

Some common side effect reactions of this tablet are:

  • Pain in joint 
  • Muscle stiffness 
  • Body ache
  • Unsteadiness 
  • Weakness
  • Difficulty in movement of hand and legs
  • Numbness
  • Burning sensations
  • Painful sensation
  • Rash 
  • Elevated AST
  • Lipodystrophy syndrome
  • Dyspepsia
  • Dizziness 
  • Peripheral neurological symptoms


Some very common side effect of atazanavir 300 mg (atazanavir sulphate) tablet are:

  • Nausea 
  • Fever 
  • Vomiting 
  • Headache
  • Extra body fat
  • Irritability
  • Back pain
  • Trouble sleeping
  • Drowsiness
  • Depression 
  • Insomnia
  • Trouble concentrating 
  • Jaundice
  • Myalgia
  • Elevated bilirubin
  • Elevated total cholesterol

Few serious or rare adverse reactions of Atazanavir Sulphate are as follows:


  • Kidney stones: patients may develop kidney stones and extreme pain over the lower abdomen, so in these cases, the drug should be discontinued and health provider information should be taken.
  • Rash: itchiness or redness of skin occurs.
  • Gallbladder problems: If pain in the middle-upper stomach area occurs then and there may be a problem in the regular functioning of the gallbladder. 
  • Hyperglycemia: elevation in blood sugar level. 
  • Hepatosplenomegaly: swelling and enlargement of liver or spleen might be caused due to uptake of atazanavir sulphate tablet. 
  • Edema: puffiness caused by fluid trapped in body cells.
  • Eczema: Rash or itchy inflammation that occurs on the skin. 
  • Myopathy: negative effects on muscles occur when atazanavir sulphate tablet is used for a long duration.
  • Ketoacidosis: atazanavir can cause a serious diabetic problem in which the body produces excess acids.
  • Vasodilation: broadening of blood vessels has been noted.
  • Cardiac conduction abnormality: PR interval prolongation may occur in some patients. 
  • Hepatotoxicity: people suffering from hepatic impairment are prone to damage. 
  • Haemophilia: spontaneous bleeding may occur.

1 comment:

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    ReplyDelete